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In vitro delivery of anti-breast cancer agents directly via the mammary papilla (nipple).
Then the doctor wants to chase side effects with other prescriptions, one being topical estrogen which is what we are attempting to block with the tamoxifen!
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Physicians rated overall cosmesis, breast pain, breast edema, and skin-color changes as significantly worse during the first two years of follow-up in the group given tamoxifen plus irradiation than in the tamoxifen group; however, by the four-year assessment, the differences were no longer significant.
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