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Substitutions of A, E, and N for D371 of bovSERPINA3-3 and D for E376 of bovSERPINA3-7 were achieved by polymerization chain reaction (PCR) site directed-mutagenesis to generate bovSERPINA3-3D371A, bovSERPINA3-3D371E, bovSERPINA3-3D371N, and bovSERPINA3-7E376D mutants.
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