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Typical pharmaceutically acceptable salts include those salts prepared by reaction of a compound of this invention with an inorganic or organic acid, or an organic base, depending on the substituents present on the compounds of the invention.

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Analyses were performed using Dynafit and kinetic parameters for each model were optimized to provide the best global fit to the experimental data.

Predicted interaction of compound 6A60 with DEN2V NS2B-NS3.

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Upon reexposure of the epidermis to the antigen, the sensitized T cells initiate an inflammatory cascade, causing the skin changes associated with allergic contact dermatitis.

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Experiments used the BOC-GRR-AMC substrate and were performed as described above with a 50 nM final concentration of trypsin.

Use in turtles is particularly contraindicated.

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Best practice is to feed horses small quantities multiple times daily, unless they are on full-time pasture.

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The risk of infection increases the longer the tick is attached, but can happen at any time during feeding.

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In veterinary medicine, Ivermectin is also used to treat dogs and horses infected by specific animal parasites.

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This initiates neutrophil activation, which helps in the secretion of products that are harmful to cells, such as nitric oxide and oxygen radicals that disrupt the normal function of corneal cells and lead to a loss of corneal clarity and can potentially lead to blindness.

La ivermectina actúa únicamente sobre el Sistema Nervioso Central, bloquea las vías que utilizan el glutamato o GABA, modificando la permeabilidad a los iones cloro de la membrana celular del nervio hiperpolarizándolo, resultando en una parálisis y muerte del parásito, comentó el doctor Coria.

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Protease residues that interacted with inhibitor functional groups were tabulated if the interacting atoms were within 4 Å of each other.

The inhibitors' core was an anthracene (or extended planar) scaffold and stabilizing H-bonding interactions occurred between functional groups located on the interacting edge of the inhibitor and catalytic (His51, Asp75, Ser135) and P1 pocket (Gly151, Gly153, Tyr150) residues of the protease.

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